EC - 7-epizingiberene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing]

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IntEnz Enzyme Nomenclature


Accepted name:
7-epizingiberene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing]
Other name:
ShZIS (gene name)
Systematic name:
(2Z,6Z)-farnesyl-diphosphate lyase (cyclizing; 7-epizingiberene-forming)



Isolated from the plant Solanum habrochaites. 7-epizingiberene is a whitefly repellant.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Bleeker, P. M., Mirabella, R., Diergaarde, P. J., Vandoorn, A., Tissier, A., Kant, M. R., Prins, M., de Vos, M., Haring, M. A., Schuurink, R. C.
    Improved herbivore resistance in cultivated tomato with the sesquiterpene biosynthetic pathway from a wild relative.
    Proc. Natl. Acad. Sci. U.S.A. 109: 20124-20129 (2012). [PMID: 23169639]

[EC created 2013]