EC - Terpinolene synthase

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IntEnz Enzyme Nomenclature


Accepted name:
terpinolene synthase
Other names:
Systematic name:
geranyl-diphosphate diphosphate-lyase (cyclizing, terpinolene-forming)




Requires Mg2+. Mn2+ is less effective and product ratio changes. Forms traces of other monoterpenoids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Croteau, R., Satterwhite, D. M.
    Biosynthesis of monoterpenes. Stereochemical implications of acyclic and monocyclic olefin formation by (+)- and (-)-pinene cyclases from sage.
    J. Biol. Chem. 264 : 15309-15315 (1989). [PMID: 2768265]
  2. Bohlmann, J., Phillips, M., Ramachandiran, V., Katoh, S., Croteau, R.
    cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis).
    Arch. Biochem. Biophys. 368 : 232-243 (1999). [PMID: 10441373]
  3. Faldt, J., Martin, D., Miller, B., Rawat, S., Bohlmann, J.
    Traumatic resin defense in Norway spruce (Picea abies): methyl jasmonate-induced terpene synthase gene expression, and cDNA cloning and functional characterization of (+)-3-carene synthase.
    Plant Mol. Biol. 51 : 119-133 (2003). [PMID: 12602896]
  4. Huber, D. P., Philippe, R. N., Godard, K. A., Sturrock, R. N., Bohlmann, J.
    Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii.
    Phytochemistry 66 : 1427-1439 (2005). [PMID: 15921711]
  5. Landmann, C., Fink, B., Festner, M., Dregus, M., Engel, K. H., Schwab, W.
    Cloning and functional characterization of three terpene synthases from lavender (Lavandula angustifolia).
    Arch. Biochem. Biophys. 465 : 417-429 (2007). [PMID: 17662687]

[EC created 2012]