EC 4.2.3.110 - (+)-sabinene synthase

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IntEnz Enzyme Nomenclature
EC 4.2.3.110

Names

Accepted name:
(+)-sabinene synthase
Other name:
SS
Systematic name:
geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-sabinene-forming]

Reaction

Comments:

Isolated from Salvia officinalis (sage). The recombinant enzyme gave 63% (+)-sabinene, 21% gamma-terpinene, and traces of other monoterpenoids. See EC 4.2.3.114 gamma-terpinene synthase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Wise, M. L., Savage, T. J., Katahira, E., Croteau, R.
    Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase.
    J. Biol. Chem. 273: 14891-14899 (1998). [PMID: 9614092]
  2. Peters, R. J., Croteau, R. B.
    Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases.
    Arch. Biochem. Biophys. 417: 203-211 (2003). [PMID: 12941302]

[EC 4.2.3.110 created 2012]