EC 4.2.2.8 - Heparin-sulfate lyase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 4.2.2.8

Names

Accepted name:
heparin-sulfate lyase
Other names:
heparin-sulfate eliminase
heparitin-sulfate lyase
heparitinase I
heparitinase II
Systematic name:
heparin-sulfate lyase

Reaction

Comments:

Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0015021
CAS Registry Number: 37290-86-1
UniProtKB/Swiss-Prot:

References

  1. Hovingh, P. and Linker, A.
    The enzymatic degradation of heparin and heparitin sulfate. 3. Purification of a heparitinase and a heparinase from flavobacteria.
    J. Biol. Chem. 245: 6170-6175 (1970). [PMID: 5484472]

[EC 4.2.2.8 created 1972]