EC 4.2.2.22 - Pectate trisaccharide-lyase

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IntEnz Enzyme Nomenclature
EC 4.2.2.22

Names

Accepted name:
pectate trisaccharide-lyase
Other names:
exopectate-lyase
pectate lyase A
PelA
Systematic name:
(1→4)-α-D-galacturonan reducing-end-trisaccharide-lyase

Reaction

Comments:

Differs in specificity from EC 4.2.2.9, pectate disaccharide-lyase, as the predominant action is removal of a trisaccharide rather than a disaccharide from the reducing end. Disaccharides and tetrasaccharides may also be removed [2].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Kluskens, L.D., van Alebeek, G.-J.W.M., Voragen, A.G.J., de Vos, W.M. and van der Oost, J.
    Molecular and biochemical characterization of the thermoactive family 1 pectate lyase from the hyperthermophilic bacterium Thermotoga maritima.
    Biochem. J. 370 : 651-659 (2003). [PMID: 12443532]
  2. Tamaru, Y. and Doi, R.H.
    Pectate lyase A, an enzymatic subunit of the Clostridium cellulovorans cellulosome.
    Proc. Natl. Acad. Sci. USA 98 : 4125-4129 (2001). [PMID: 11259664]
  3. Berensmeier, S., Singh, S.A., Meens, J. and Buchholz, K.
    Cloning of the pelA gene from Bacillus licheniformis 14A and biochemical characterization of recombinant, thermostable, high-alkaline pectate lyase.
    Appl. Microbiol. Biotechnol. 64 : 560-567 (2004). [PMID: 14673544]

[EC 4.2.2.22 created 2007]