EC - Levan fructotransferase (DFA-IV-forming)

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
levan fructotransferase (DFA-IV-forming)
Other names:
2,6-β-D-fructan D-fructosyl-D-fructosyltransferase (forming di-β-D-fructofuranose 2,6':2',6-dianhydride)
levan fructotransferase
2,6-β-D-fructan lyase (di-β-D-fructofuranose-2,6':2',6-dianhydride-forming)
Systematic name:
(2→6)-β-D-fructan lyase (di-β-D-fructofuranose-2,6':2',6-dianhydride-forming)



This enzyme, like EC [inulin fructotransferase (DFA-I-forming)] and EC [inulin fructotransferase (DFA-III-forming)] eliminates the fructan chain from the terminal disaccharide leaving a difructose dianhydride. These enzymes have long been known as fructotransferases, so this is retained in the accepted name. Since the transfer is intramolecular, the reaction is an elimination and, hence, the enzyme is a lyase, belonging in EC 4.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033996


  1. Song, K.B., Bae, K.S., Lee, Y.B., Lee, K.Y. and Rhee, S.K.
    Characteristics of levan fructotransferase from Arthrobacter ureafaciens K2032 and difructose anhydride IV formation from levan.
    Enzyme Microb. Technol. 27 : 212-218 (2000).
  2. Jang, K.H., Ryu, E.J., Park, B.S., Song, K.B., Kang, S.A., Kim, C.H., Uhm, T.B., Park, Y.I. and Rhee, S.K.
    Levan fructotransferase from Arthrobacter oxydans J17-21 catalyzes the formation of the di-D-fructose dianhydride IV from levan.
    J. Agric. Food Chem. 51 : 2632-2636 (2003). [PMID: 12696949]
  3. Saito, K. and Tomita, F.
    Difructose anhydrides: Their mass-production and physiological functions.
    Biosci. Biotechnol. Biochem. 64 : 1321-1327 (2000). [PMID: 10945246]

[EC created 2004]