EC 4.2.2.15 - Anhydrosialidase

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IntEnz Enzyme Nomenclature
EC 4.2.2.15

Names

Accepted name:
anhydrosialidase
Other names:
anhydroneuraminidase
sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing)
sialidase L
Systematic name:
glycoconjugate sialyl-lyase (2,7-cyclizing)

Reaction

Comments:

Also acts on N-glycolylneuraminate glycosides. cf. EC 3.2.1.18 (exo-α-sialidase) and EC 3.2.1.129 (endo-α-sialidase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033995
CAS Registry Number: 157857-11-9
UniProtKB/Swiss-Prot:

References

  1. Li, Y.-T., Nakagawa, H., Ross, S.A., Hansson, G.C. and Li, S.C.
    A novel sialidase which releases 2,7-anhydro-α-N-acetylneuraminic acid from sialoglycoconjugates.
    J. Biol. Chem. 265: 21629-21633 (1990). [PMID: 2254319]

[EC 4.2.2.15 created 1992 as EC 3.2.1.138, transferred 2003 to EC 4.2.2.15]