EC - Arogenate dehydratase

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IntEnz Enzyme Nomenclature


Accepted name:
arogenate dehydratase
Other names:
carboxycyclohexadienyl dehydratase
L-arogenate hydro-lyase (decarboxylating)
Systematic name:
L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)



Also acts on prephenate and D-prephenyllactate. cf. EC prephenate dehydratase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00798
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047769
UniProtKB/Swiss-Prot: (11) [show] [UniProt]


  1. Fischer, R. and Jensen, R.
    Arogenate dehydratase.
    Methods Enzymol. 142 : 495-502 (1987). [PMID: 3600377]
  2. Zamir, L.O., Tiberio, R., Devor, K.A., Sauriol, F., Ahmad, S. and Jensen, R.A.
    Structure of D-prephenyllactate. A carboxycyclohexadienyl metabolite from Neurospora crassa.
    J. Biol. Chem. 263 : 17284-17290 (1988). [PMID: 2972718]
  3. Siehl, D.L. and Conn, E.E.
    Kinetic and regulatory properties of arogenate dehydratase in seedlings of Sorghum bicolor (L.) Moench.
    Arch. Biochem. Biophys. 260 : 822-829 (1988). [PMID: 3124763]

[EC created 1992, modified 2005]