EC - Dihydroxy-acid dehydratase

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IntEnz Enzyme Nomenclature


Accepted name:
dihydroxy-acid dehydratase
Other names:
2,3-dihydroxyisovalerate dehydratase
α,β-dihydroxyacid dehydratase
α,β-dihydroxyisovalerate dehydratase
acetohydroxyacid dehydratase
dihydroxy acid dehydrase
2,3-dihydroxy-acid hydro-lyase
Systematic name:
2,3-dihydroxy-methylbutanoate hydro-lyase (3-methyl-2-oxobutanoate-forming)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00690
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004160
CAS Registry Number: 9024-32-2
UniProtKB/Swiss-Prot: (583) [show] [UniProt]


  1. Kanamori, M. and Wixom, R.L.
    Studies in valine biosynthesis. V. Characteristics of the purified dihydroxyacid dehydratase from spinach leaves.
    J. Biol. Chem. 238 : 998-1005 (1963). [PMID: 13962154]
  2. Myers, J.W.
    Dihydroxy acid dehydrase: an enzyme involved in the biosynthesis of isoleucine and valine.
    J. Biol. Chem. 236 : 1414-1418 (1961). [PMID: 13727223]

[EC created 1961]