EC - trans-L-3-hydroxyproline dehydratase

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IntEnz Enzyme Nomenclature


Accepted name:
trans-L-3-hydroxyproline dehydratase
Other name:
trans-L-3-hydroxyproline hydro-lyase
Systematic name:
trans-3-hydroxy-Lproline hydro-lyase (1-pyrroline-2-carboxylate-forming)



Highly specific.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050346
UniProtKB/Swiss-Prot: (23) [show] [UniProt]


  1. Ramaswamy, S.G.
    Conversion of 3-hydroxyproline to proline in the rat requires reduced pyridine-nucleotides.
    Fed. Proc. 42 : 2232 (1983).
  2. Visser, W. F., Verhoeven-Duif, N. M., de Koning, T. J.
    Identification of a Human trans-3-Hydroxy-L-proline Dehydratase, the First Characterized Member of a Novel Family of Proline Racemase-like Enzymes.
    J. Biol. Chem. 287 : 21654-21662 (2012). [PMID: 22528483]

[EC created 1984]