EC 4.2.1.74 - Long-chain-enoyl-CoA hydratase

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IntEnz Enzyme Nomenclature
EC 4.2.1.74

Names

Accepted name:
long-chain-enoyl-CoA hydratase
Other name:
long-chain enoyl coenzyme A hydratase
Systematic name:
long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase

Reaction

Comments:

Acts in the reverse direction. The best substrate is oct-3-enoyl-CoA. Unlike EC 4.2.1.17 enoyl-CoA hydratase, it does not act on crotonoyl-CoA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016508
CAS Registry Number: 62009-81-8

References

  1. Fong, J.C. and Schulz, H.
    Purification and properties of pig heart crotonase and the presence of short chain and long chain enoyl coenzyme A hydratases in pig and guinea pig tissues.
    J. Biol. Chem. 252 : 542-547 (1977). [PMID: 833142]
  2. Schulz, H.
    Long chain enoyl coenzyme A hydratase from pig heart.
    J. Biol. Chem. 249 : 2704-2709 (1974). [PMID: 4828315]

[EC 4.2.1.74 created 1981]