EC 4.2.1.45 - CDP-glucose 4,6-dehydratase

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IntEnz Enzyme Nomenclature
EC 4.2.1.45

Names

Accepted name:
CDP-glucose 4,6-dehydratase
Other names:
CDPglucose 4,6-dehydratase
CDPglucose 4,6-hydro-lyase
cytidine diphosphoglucose oxidoreductase
CDP-glucose 4,6-hydro-lyase
Systematic name:
CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)

Reaction

Cofactor

Comments:

Requires bound NAD+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047733
CAS Registry Number: 37259-55-5
UniProtKB/Swiss-Prot:

References

  1. Hey, A.E. and Elbein, A.D.
    Biosynthesis of tyvelose. The purification and properties of cytidine diphosphate D-glucose oxidoreductase.
    J. Biol. Chem. 241: 5473-5478 (1966). [PMID: 4380946]
  2. Matsuhashi, S., Matsuhashi, M., Brown, J.G. and Strominger, J.L.
    Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. 3. Cytidine diphosphate D-glucose oxidoreductase.
    J. Biol. Chem. 241: 4283-4287 (1966). [PMID: 4288651]
  3. Melo, A., Elliott, H. and Glaser, L.
    The mechanism of 6-deoxyhexose synthesis. I. Intramolecular hydrogen transfer catalyzed by deoxythymidine diphosphate D-glucose oxidoreductase.
    J. Biol. Chem. 243: 1467-1474 (1968). [PMID: 4869560]

[EC 4.2.1.45 created 1972]