EC 4.2.1.30 - Glycerol dehydratase

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IntEnz Enzyme Nomenclature
EC 4.2.1.30

Names

Accepted name:
glycerol dehydratase
Other names:
glycerol dehydrase
glycerol hydro-lyase
Systematic name:
glycerol hydro-lyase (3-hydroxypropanal-forming)

Reaction

Cofactor

Comments:

Two different forms of the enzyme have been described. One form requires a cobamide coenzyme, while the other is a glycyl radical enzyme.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0046405
CAS Registry Number: 9077-68-3
UniProtKB/Swiss-Prot:

References

  1. Forage, R.G. and Foster, M.A.
    Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases.
    J. Bacteriol. 149 : 413-419 (1982). [PMID: 7035429]
  2. Schneider, Z., Larsen, E.G., Jacobsen, G., Johnson, B.C. and Pawelkiewicz, J.
    Purification and properties of glycerol dehydrase.
    J. Biol. Chem. 245 : 3388-3396 (1970). [PMID: 4989992]
  3. Schneider, Z. and Pawelkiewicz, J.
    The properties of glycerol dehydratase isolated from Aerobacter aerogenes, and the properties of the apoenzyme subunits.
    Acta Biochim. Pol. 13 : 311-328 (1966). [PMID: 5962440]
  4. Smiley, K.L. and Sobolov, M.
    A cobamide-requiring glycerol dehydrase from an acrolein-forming Lactobacillus.
    Arch. Biochem. Biophys. 97 : 538-543 (1962). [PMID: 14039344]
  5. O'Brien, J. R., Raynaud, C., Croux, C., Girbal, L., Soucaille, P., Lanzilotta, W. N.
    Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization.
    Biochemistry 43 : 4635-4645 (2004). [PMID: 15096031]

[EC 4.2.1.30 created 1972]