EC 4.2.1.103 - Cyclohexyl-isocyanide hydratase

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IntEnz Enzyme Nomenclature
EC 4.2.1.103

Names

Accepted name:
cyclohexyl-isocyanide hydratase
Other names:
isonitrile hydratase
N-cyclohexylformamide hydro-lyase
Systematic name:
N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)

Reaction

Comments:

The enzyme from Pseudomonas putida strain N19-2 can also catalyse the hydration of other isonitriles to the corresponding N-substituted formamides. The enzyme has no metal requirements.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050549
UniProtKB/Swiss-Prot:

References

  1. Goda, M., Hashimoto, Y., Shimizu, S. and Kobayashi, M.
    Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage.
    J. Biol. Chem. 276: 23480-23485 (2001). [PMID: 11306561]

[EC 4.2.1.103 created 2001]