EC - Citramalate lyase

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IntEnz Enzyme Nomenclature


Accepted name:
citramalate lyase
Other names:
(+)-citramalate pyruvate-lyase
(S)-citramalate lyase
citramalate pyruvate lyase
citramalate pyruvate-lyase
citramalate synthase
citramalate synthetase
citramalic synthase
citramalic-condensing enzyme
(3S)-citramalate pyruvate-lyase
(2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase
Systematic name:
(2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase (acetate-forming)



The enzyme can be dissociated into components, two of which are identical with EC (citramalate CoA-transferase) and EC (citramalyl-CoA lyase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047776
CAS Registry Number: 9027-93-4


  1. Barker, H.A.
    Citramalate lyase of Clostridium tetanomorphum.
    Arch. Mikrobiol. 59: 4-12 (1967). [PMID: 4301387]
  2. Dimroth, P., Buckel, W., Loyal, R. and Eggerer, H.
    Isolation and function of the subunits of citramalate lyase and formation of hybrids with the subunits of citrate lyase.
    Eur. J. Biochem. 80: 469-477 (1977). [PMID: 923590]

[EC created 1972]