EC 4.1.3.1 - Isocitrate lyase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 4.1.3.1
Names
Accepted name:
isocitrate lyase
Other
names:
threo-DS-isocitrate glyoxylate-lyase
isocitrase
isocitratase
isocitritase
ICL
isocitrate glyoxylate-lyase
isocitrase
isocitratase
isocitritase
ICL
isocitrate glyoxylate-lyase
Systematic name:
isocitrate glyoxylate-lyase (succinate-forming)
Reaction
-
13245 [IUBMB]D-threo-isocitrateName origin: UniProt - CHECKED (C)Formula: C6H5O7
Charge: -3ChEBI compound status: CHECKED (C)=glyoxylateName origin: UniProt - CHECKED (C)Formula: C2HO3
Charge: -1ChEBI compound status: CHECKED (C)
Comments:
The isomer of isocitrate involved is (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate [3].
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
NIST 74
,
UniPathway
Protein domains and families:
PROSITE:PDOC00145
Gene Ontology:
GO:0004451
CAS Registry Number:
9045-78-7
References
-
Crystallisation and some properties of isocitrate lyase from Pseudomonas indigofera.J. Biol. Chem. 238 : 1737-1742 (1963).
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Isocitrate lyase from Pseudomonas indigofera. I. Preparation, amino acid composition and molecular weight.Biochim. Biophys. Acta 96 : 114-122 (1965). [PMID: 14285253]
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A suggested new nomenclature for the isomers of isocitric acid.J. Biol. Chem. 237 : 1739-1741 (1962). [PMID: 13925783]
[EC 4.1.3.1 created 1961]