EC - Tagatose-bisphosphate aldolase

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IntEnz Enzyme Nomenclature


Accepted name:
tagatose-bisphosphate aldolase
Other names:
tagatose 1,6-diphosphate aldolase
D-tagatose-1,6-bisphosphate aldolase
D-tagatose-1,6-bisphosphate triosephosphate lyase
Systematic name:
D-tagatose 1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)



Enzyme activity is stimulated by certain divalent cations. It is involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0009025
CAS Registry Number: 39433-95-9
UniProtKB/Swiss-Prot: (108) [show] [UniProt]


  1. Anderson, R.L., Markwell, J.P.
    D-Tagatose-1,6-bisphosphate aldolase (Class II) from Klebsiella pneumoniae.
    Methods Enzymol. 90 : 323-324 (1982).
  2. Van Rooijen, R.J., Van Schalkwijk, S., De Vos, W.M.
    Molecular cloning, characterization, and nucleotide sequence of the tagatose 6-phosphate pathway gene cluster of the lactose operon of Lactococcus lactis.
    J. Biol. Chem. 266 : 7176-7181 (1991). [PMID: 1901863]

[EC created 1999]