EC 4.1.1.95 - L-glutamyl-[BtrI acyl-carrier protein] decarboxylase

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IntEnz Enzyme Nomenclature
EC 4.1.1.95

Names

Accepted name:
L-glutamyl-[BtrI acyl-carrier protein] decarboxylase
Other name:
btrK (gene name)
Systematic name:
L-glutamyl-[BtrI acyl-carrier protein] carboxy-lyase

Reaction

Cofactor

Comments:

Binds pyridoxal 5'-phosphate. Catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family. Has very low activity with substrates not bound to an acyl-carrier protein.

Catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family. Has very low activity with substrates not bound to an acyl-carrier protein.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Li, Y., Llewellyn, N. M., Giri, R., Huang, F., Spencer, J. B.
    Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway.
    Chem. Biol. 12 : 665-675 (2005). [PMID: 15975512]

[EC 4.1.1.95 created 2012]