EC 4.1.1.93 - Pyrrole-2-carboxylate decarboxylase

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IntEnz Enzyme Nomenclature
EC 4.1.1.93

Names

Accepted name:
pyrrole-2-carboxylate decarboxylase
Systematic name:
pyrrole-2-carboxylate carboxy-lyase

Reactions

Comments:

The enzyme catalyses both the carboxylation and decarboxylation reactions. However, while bicarbonate is the preferred substrate for the carboxylation reaction, decarboxylation produces carbon dioxide. The enzyme is activated by carboxylic acids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0034941

References

  1. Wieser, M., Fujii, N., Yoshida, T., Nagasawa, T.
    Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910.
    Eur. J. Biochem. 257: 495-499 (1998). [PMID: 9826198]
  2. Omura, H., Wieser, M., Nagasawa, T.
    Pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910, an organic-acid-requiring enzyme.
    Eur. J. Biochem. 253: 480-484 (1998). [PMID: 9654100]
  3. Wieser, M., Yoshida, T. and Nagasawa, T.
    Microbial synthesis of pyrrole-2-carboxylate by Bacillus megaterium PYR2910.
    Tetrahedron Lett. 39: 4309-4310 (1998).

[EC 4.1.1.93 created 2011]