EC - Malonyl-CoA decarboxylase

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IntEnz Enzyme Nomenclature


Accepted name:
malonyl-CoA decarboxylase
Other names:
malonyl coenzyme A decarboxylase
malonyl-CoA carboxy-lyase
Systematic name:
malonyl-CoA carboxy-lyase (acetyl-CoA-forming)



Specific for malonyl-CoA. The enzyme from Pseudomonas ovalis also catalyses the reaction of EC malonate CoA-transferase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050080
CAS Registry Number: 9024-99-1


  1. Buckner, J.S., Kolattudy, P.E. and Poulose, A.J.
    Purification and properties of malonyl-coenzyme A decarboxylase, a regulatory enzyme from the uropygial gland of goose.
    Arch. Biochem. Biophys. 177 : 539-551 (1976). [PMID: 827976]
  2. Takamura, Y. and Kitayama, Y.
    Purification and some properties of malonate decarboxylase from Pseudomonas ovalis - an oligomeric enzyme with bifunctional properties.
    Biochem. Int. 3 : 483-491 (1981).

[EC created 1961, deleted 1972, reinstated 1978]