EC - Acetylenedicarboxylate decarboxylase

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IntEnz Enzyme Nomenclature


Accepted name:
acetylenedicarboxylate decarboxylase
Other names:
acetylenedicarboxylate hydrase
acetylenedicarboxylate hydratase
acetylenedicarboxylate carboxy-lyase
Systematic name:
acetylenedicarboxylate carboxy-lyase (pyruvate-forming)



The mechanism appears to involve hydration of the acetylene and decarboxylation of the oxaloacetic acid formed, although free oxaloacetate is not an intermediate. It is thus analogous to EC (acetylenecarboxylate hydratase) in its mechanism. Formerly EC

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050476
CAS Registry Number: 72561-10-5


  1. Yamada, E.W. and Jakoby, W.B.
    Enzymatic utilization of acetylenic compounds. I. An enzyme converting acetylenedicarboxylic acid to pyruvate.
    J. Biol. Chem. 233: 706-711 (1958). [PMID: 13575441]

[EC created 1978 as EC, transferred 2000 to EC]