EC 4.1.1.71 - 2-oxoglutarate decarboxylase

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IntEnz Enzyme Nomenclature
EC 4.1.1.71

Names

Accepted name:
2-oxoglutarate decarboxylase
Other names:
α-ketoglutarate decarboxylase
α-ketoglutaric decarboxylase
oxoglutarate decarboxylase
pre-2-oxoglutarate decarboxylase
2-oxoglutarate carboxy-lyase
Systematic name:
2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)

Reaction

Cofactor

Comments:

Requires thiamine diphosphate. Highly specific.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008683
CAS Registry Number: 37205-42-8
UniProtKB/Swiss-Prot: (13) [show] [UniProt]

References

  1. Shigeoka, S., Onishi, T., Maeda, K., Nakano, Y. and Kitaoka, S.
    Occurrence of thiamin pyrophosphate-dependent 2-oxoglutarate decarboxylase in mitochondria of Euglena gracilis.
    FEBS Lett. 195: 43-47 (1986).

[EC 4.1.1.71 created 1989]