EC 4.1.1.65 - Phosphatidylserine decarboxylase

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IntEnz Enzyme Nomenclature
EC 4.1.1.65

Names

Accepted name:
phosphatidylserine decarboxylase
Other names:
PS decarboxylase
phosphatidyl-L-serine carboxy-lyase
Systematic name:
phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein. In Escherichia coli, the prosthetic group is a pyruvoyl group.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004609
CAS Registry Number: 9054-78-8
UniProtKB/Swiss-Prot: (479) [show] [UniProt]

References

  1. Kanfer, J. and Kennedy, E.P.
    Metabolism and function of bacterial lipids. II. Biosynthesis of phospholipids in Escherichia coli.
    J. Biol. Chem. 239 : 1720-1726 (1964). [PMID: 14213340]
  2. Satre, M. and Kennedy, E.P.
    Identification of bound pyruvate essential for the activity of phosphatidylserine decarboxylase of Escherichia coli.
    J. Biol. Chem. 253 : 479-483 (1978). [PMID: 338609]

[EC 4.1.1.65 created 1976]