EC 4.1.1.45 - Aminocarboxymuconate-semialdehyde decarboxylase

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IntEnz Enzyme Nomenclature
EC 4.1.1.45

Names

Accepted name:
aminocarboxymuconate-semialdehyde decarboxylase
Other names:
α-amino-β-carboxymuconate-ε-semialdehade decarboxylase
α-amino-β-carboxymuconate-ε-semialdehyde β-decarboxylase
picolinic acid carboxylase
picolinic acid decarboxylase
2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase
Systematic name:
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)

Reaction

Comments:

Product rearranges non-enzymically to picolinate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0001760
CAS Registry Number: 37289-47-7
UniProtKB/Swiss-Prot:

References

  1. Ichiyama, A., Nakamura, S., Kawai, H., Honjo, T., Nishizuka, Y., Hayaishi, O. and Senoh, S.
    Studies on the metabolism of the benzene ring of tryptophan in mammalian tissues. ii. enzymic formation of α-aminomuconic acid from 3-hydroxyanthranilic acid.
    J. Biol. Chem. 240: 740-749 (1965). [PMID: 14275130]

[EC 4.1.1.45 created 1972]