EC 3.8.1.9 - (R)-2-haloacid dehalogenase

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IntEnz Enzyme Nomenclature
EC 3.8.1.9

Names

Accepted name:
(R)-2-haloacid dehalogenase
Other names:
2-haloalkanoic acid dehalogenase [ambiguous]
2-haloalkanoid acid halidohydrolase [ambiguous]
D-2-haloacid dehalogenase
D-DEX
Systematic name:
(R)-2-haloacid halidohydrolase

Reaction

Comments:

Acts on acids of short chain lengths, C2 to C4, with inversion of configuration at C-2. (see also EC 3.8.1.2, (S)-2-haloacid dehalogenase, EC 3.8.1.10, 2-haloacid dehalogenase (configuration-inverting) and EC 3.8.1.11, 2-haloacid dehalogenase (configuration-retaining)).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033975
CAS Registry Number: 119345-29-8
UniProtKB/Swiss-Prot:

References

  1. Smith, J.M., Harrison, K. and Colby, J.
    Purification and characterization of D-2-haloacid dehalogenase from Pseudomonas putida strain AJ1/23.
    J. Gen. Microbiol. 136 : 881-886 (1990). [PMID: 2380688]
  2. Leigh, J.A., Skinner, A.J. and Cooper, R.A.
    Partial purification, stereospecificity and stoichiometry of three dehalogenases from a Rhizobium species.
    FEMS Microbiol. Lett. 49 : 353-356 (1988).
  3. Soda, K., Kurihara, T., Liu, J.-Q., Nardi-Dei, V., Park, C., Miyagi, M., Tsunasawa, S. and Esaki, N.
    Bacterial 2-haloacid dehalogenases: Structures and catalytic properties.
    Pure Appl. Chem. 68 : 2097-2103 (1996).

[EC 3.8.1.9 created 2003]