EC - 4-chlorobenzoyl-CoA dehalogenase

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IntEnz Enzyme Nomenclature


Accepted name:
4-chlorobenzoyl-CoA dehalogenase
Systematic name:
4-chlorobenzoyl CoA chlorohydrolase



specific for dehalogenation at the 4-position. Can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position. This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018787


  1. Chang, K.H., Liang, P.H., Beck, W., Scholten, J.D., Dunaway-Mariano, D.
    Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3.
    Biochemistry 31 : 5605-5610 (1992). [PMID: 1610806]
  2. Crooks, G.P. and Copley, S.D.
    Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1.
    Biochemistry 33 : 11645-11649 (1994). [PMID: 7918379]

[EC created 1999]