EC - 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

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IntEnz Enzyme Nomenclature


Accepted name:
2,6-dioxo-6-phenylhexa-3-enoate hydrolase
Other name:
HOHPDA hydrolase
Systematic name:
2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase



Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond. Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018774
CAS Registry Number: 102925-38-2
UniProtKB/Swiss-Prot: (10) [show] [UniProt]


  1. Omori, T., Sugimura, K., Ishigooka, H. and Minoda, Y.
    Purification and some properties of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolyzing enzyme from Pseudomonas cruciviae S93 B1 involved in the degradation of biphenyl.
    Agric. Biol. Chem. 50 : 931-937 (1986).

[EC created 1989]