EC - Dynamin GTPase

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IntEnz Enzyme Nomenclature


Accepted name:
dynamin GTPase
Systematic name:
GTP phosphohydrolase (vesicle-releasing)



An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00362
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (103) [show] [UniProt]


  1. Warnock, D.E. and Schmid, S.L.
    Dynamin GTPase, a force-generating molecular switch.
    Bioessays 18 : 885-893 (1996). [PMID: 8939066]
  2. McClure, S.J. and Robinson, P.J.
    Dynamin, endocytosis and intracellular signalling.
    Mol. Membr. Biol. 13 : 189-215 (1996). [PMID: 9116759]
  3. Oh, P., McIntosh, D.P. and Schnitzer, J.E.
    Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium.
    J. Cell Biol. 141 : 101-114 (1998). [PMID: 9531551]

[EC created 2000 as EC, transferred 2003 to EC]