IntEnz

EC 3.6.3.2 - Mg²⁺-importing ATPase

IntEnz Enzyme Nomenclature
EC 3.6.3.2

Names

Reaction

• 10260 [IUBMB]
  ATP

  ATP

  Name origin: UniProt - CHECKED (C)

  CHEBI:30616

  Formula: C10H12N5O13P3
  Charge: -4

  ChEBI compound status: CHECKED (C)

  

  +

  H₂O

  H2O

  Name origin: UniProt - CHECKED (C)

  CHEBI:15377

  Formula: H2O
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  Mg²⁺

  Mg(2+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:18420

  Formula: Mg
  Charge: 2

  ChEBI compound status: CHECKED (C)

  

  OUT

  =

  ADP

  ADP

  Name origin: UniProt - CHECKED (C)

  CHEBI:456216

  Formula: C10H12N5O10P2
  Charge: -3

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  Mg²⁺

  Mg(2+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:18420

  Formula: Mg
  Charge: 2

  ChEBI compound status: CHECKED (C)

  

  IN

  +

  phosphate

  phosphate

  Name origin: UniProt - CHECKED (C)

  CHEBI:43474

  Formula: HO4P
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

Cofactor

• Mg²⁺

Comments:

A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme occurs in both Gram-positive and Gram-negative bacteria, and three types are known, designated as CorA, MgtA and MgtB. The CorA itself is not an ATPase but an Mg²⁺ transporter.

Links to other databases

References

1. Tao, T., Snavely, M.D., Farr, S.G. and Maguire, M.E.
   Magnesium transport in Salmonella typhimurium: mtgA encodes a P-type ATPase and is regulated by Mg²⁺ in a manner similar to that of the mgtB P-type ATPase.
   J. Bacteriol. 177: 2654-2662 (1995). [PMID: 7751273]
2. Snavely, M. D., Miller, C. G., Maguire, M. E.
   The mgtB Mg2+ transport locus of Salmonella typhimurium encodes a P-type ATPase.
   J. Biol. Chem. 266: 815-823 (1991). [PMID: 1824701]

[EC 3.6.3.2 created 2000, modified 2001]