IntEnz

EC 3.6.1.8 - ATP diphosphatase

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IntEnz Enzyme Nomenclature
EC 3.6.1.8

Names

Accepted name:

ATP diphosphatase

Other names:

ATP diphosphohydrolase [ambiguous]
ATP pyrophosphatase
ATPase [ambiguous]
adenosine triphosphate pyrophosphatase

Systematic name:

ATP diphosphohydrolase (diphosphate-forming)

Reactions

14245 [IUBMB]

ATP

ATP

Name origin: UniProt - CHECKED (C)

CHEBI:30616

Formula: C10H12N5O13P3
Charge: -4

ChEBI compound status: CHECKED (C)

+

H₂O

H2O

Name origin: UniProt - CHECKED (C)

CHEBI:15377

Formula: H2O
Charge: 0

ChEBI compound status: CHECKED (C)

=

AMP

AMP

Name origin: UniProt - CHECKED (C)

CHEBI:456215

Formula: C10H12N5O7P
Charge: -2

ChEBI compound status: CHECKED (C)

+

diphosphate

diphosphate

Name origin: UniProt - CHECKED (C)

CHEBI:33019

Formula: HO7P2
Charge: -3

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)
27762

CTP

CTP

Name origin: UniProt - CHECKED (C)

CHEBI:37563

Formula: C9H12N3O14P3
Charge: -4

ChEBI compound status: CHECKED (C)

+

H₂O

H2O

Name origin: UniProt - CHECKED (C)

CHEBI:15377

Formula: H2O
Charge: 0

ChEBI compound status: CHECKED (C)

=

CMP

CMP

Name origin: UniProt - CHECKED (C)

CHEBI:60377

Formula: C9H12N3O8P
Charge: -2

ChEBI compound status: CHECKED (C)

+

diphosphate

diphosphate

Name origin: UniProt - CHECKED (C)

CHEBI:33019

Formula: HO7P2
Charge: -3

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)
29399

H₂O

H2O

Name origin: UniProt - CHECKED (C)

CHEBI:15377

Formula: H2O
Charge: 0

ChEBI compound status: CHECKED (C)

+

ITP

ITP

Name origin: UniProt - CHECKED (C)

CHEBI:61402

Formula: C10H11N4O14P3
Charge: -4

ChEBI compound status: CHECKED (C)

=

diphosphate

diphosphate

Name origin: UniProt - CHECKED (C)

CHEBI:33019

Formula: HO7P2
Charge: -3

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

IMP

IMP

Name origin: UniProt - CHECKED (C)

CHEBI:58053

Formula: C10H11N4O8P
Charge: -2

ChEBI compound status: CHECKED (C)
29395

H₂O

H2O

Name origin: UniProt - CHECKED (C)

CHEBI:15377

Formula: H2O
Charge: 0

ChEBI compound status: CHECKED (C)

+

UTP

UTP

Name origin: UniProt - CHECKED (C)

CHEBI:46398

Formula: C9H11N2O15P3
Charge: -4

ChEBI compound status: CHECKED (C)

=

diphosphate

diphosphate

Name origin: UniProt - CHECKED (C)

CHEBI:33019

Formula: HO7P2
Charge: -3

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

+

UMP

UMP

Name origin: UniProt - CHECKED (C)

CHEBI:57865

Formula: C9H11N2O9P
Charge: -2

ChEBI compound status: CHECKED (C)
29391

GTP

GTP

Name origin: UniProt - CHECKED (C)

CHEBI:37565

Formula: C10H12N5O14P3
Charge: -4

ChEBI compound status: CHECKED (C)

+

H₂O

H2O

Name origin: UniProt - CHECKED (C)

CHEBI:15377

Formula: H2O
Charge: 0

ChEBI compound status: CHECKED (C)

=

diphosphate

diphosphate

Name origin: UniProt - CHECKED (C)

CHEBI:33019

Formula: HO7P2
Charge: -3

ChEBI compound status: CHECKED (C)

+

GMP

GMP

Name origin: UniProt - CHECKED (C)

CHEBI:58115

Formula: C10H12N5O8P
Charge: -2

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

Comments:

Also acts on ITP, GTP, CTP and UTP.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

Gene Ontology: GO:0047693

CAS Registry Number: 37289-25-1

UniProtKB/Swiss-Prot:

P0AEY4

MAZG_ECO57

P0AEY3

MAZG_ECOLI

P44723

MAZG_HAEIN

A0R3C4

MAZG_MYCS2

P96379

MAZG_MYCTU

References

Heppel, L.A. and Hilmoe, R.J.

Mechanism of enzymatic hydrolysis of adenosinetriphosphate.

J. Biol. Chem. 202: 217-226 (1953).
Johnson, M., Kaye, M.A.G., Hems, R. and Krebs, H.A.

Enzymic hydrolysis of adenosine phosphates by cobra venom.

Biochem. J. 54: 625-629 (1953).

[EC 3.6.1.8 created 1961]

EC 3 - Hydrolases