EC 3.6.1.64 - Inosine diphosphate phosphatase

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IntEnz Enzyme Nomenclature
EC 3.6.1.64

Names

Accepted name:
inosine diphosphate phosphatase
Other names:
(deoxy)inosine diphosphatase
NUDT16
Systematic name:
inosine diphosphate phosphatase

Reactions

Comments:

The human enzyme also hydrolyses GDP and dGDP, and to a lesser extent ITP, dITP and XTP.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Iyama, T., Abolhassani, N., Tsuchimoto, D., Nonaka, M., Nakabeppu, Y.
    NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest.
    Nucleic Acids Res. 38: 4834-4843 (2010). [PMID: 20385596]

[EC 3.6.1.64 created 2013]