EC - DUTP diphosphatase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
dUTP diphosphatase
Other names:
dUTP pyrophosphatase
desoxyuridine 5'-triphosphatase
desoxyuridine 5'-triphosphate nucleotidohydrolase
Systematic name:
dUTP nucleotidohydrolase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004170
CAS Registry Number: 37289-34-2
UniProtKB/Swiss-Prot: (558) [show] [UniProt]


  1. Bertani, L.E., Häggmark, A. and Reichard, P.
    Enzymatic synthesis of deoxyribonucleotides. II. Formation and interconversion of deoxyuridine phosphates.
    J. Biol. Chem. 238: 3407-3413 (1963).
  2. Giroir, L.E. and Deutsch, W.A.
    Drosophila deoxyuridine triphosphatase. Purification and characterization.
    J. Biol. Chem. 262: 130-134 (1987). [PMID: 3025197]
  3. Greenberg, G.R. and Somerville, R.L.
    Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli.
    Proc. Natl. Acad. Sci. USA 48: 247-257 (1962).
  4. Grindey, G.B. and Nichol, C.A.
    Mammalian deoxyuridine 5'-triphosphate pyrophosphatase.
    Biochim. Biophys. Acta 240: 180-183 (1971). [PMID: 5105331]

[EC created 1972]