EC 220.127.116.11 - Hydroxydechloroatrazine ethylaminohydrolase
IntEnz Enzyme Nomenclature
- hydroxyatrazine + H2O = N-isopropylammelide + ethylamine
Contains Zn2+. This bacterial enzyme is involved in degradation of the herbicide atrazine. The enzyme has a broad substrate range, and requires a monohydroxylated S-triazine ring with a minimum of one primary or secondary amine substituent and either a chloride or amine leaving group. It catalyses both deamination and dechlorination reactions.
Links to other databases
The atzB gene of Pseudomonas sp. strain ADP encodes the second enzyme of a novel atrazine degradation pathway.Appl. Environ. Microbiol. 63 : 916-923 (1997). [PMID: 9055410]
Hydroxyatrazine N-ethylaminohydrolase (AtzB): an amidohydrolase superfamily enzyme catalyzing deamination and dechlorination.J. Bacteriol. 189 : 6989-6997 (2007). [PMID: 17660279]
[EC 18.104.22.168 created 2000 as EC 22.214.171.124, transferred 2016 to EC 126.96.36.199]