EC 3.5.4.35 - TRNA(cytosine8) deaminase

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IntEnz Enzyme Nomenclature
EC 3.5.4.35

Names

Accepted name:
tRNA(cytosine8) deaminase
Other name:
CDAT8
Systematic name:
tRNA(cytosine8) aminohydrolase

Reaction

Comments:

The enzyme from Methanopyrus kandleri specifically catalyses the deamimation of cytosine at poition 8 of tRNA in 30 different tRNAs. This cytosine-to-uracil editing guarantees the proper folding and functionality of the tRNAs.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Randau, L., Stanley, B. J., Kohlway, A., Mechta, S., Xiong, Y., Soll, D.
    A cytidine deaminase edits C to U in transfer RNAs in Archaea.
    Science 324 : 657-659 (2009). [PMID: 19407206]

[EC 3.5.4.35 created 2013]