EC - Methenyltetrahydromethanopterin cyclohydrolase

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IntEnz Enzyme Nomenclature


Accepted name:
methenyltetrahydromethanopterin cyclohydrolase
Other names:
5,10-methenyltetrahydromethanopterin cyclohydrolase
N5,N10-methenyltetrahydromethanopterin cyclohydrolase
methenyl-H4MPT cyclohydrolase
5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing)
Systematic name:
5,10-methenyltetrahydromethanopterin 10-hydrolase (ring-opening)



Methanopterin is a pterin analogue. The enzyme is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018759
UniProtKB/Swiss-Prot: (38) [show] [UniProt]


  1. Donnelly, M.I., Escalante-Semerena, J.C., Rinehart, K.L., Jr. and Wolfe, R.S.
    Methenyl-tetrahydromethanopterin cyclohydrolase in cell extracts of Methanobacterium.
    Arch. Biochem. Biophys. 242: 430-439 (1985). [PMID: 4062290]

[EC created 1989]