EC 3 - Hydrolases
EC 3.5 - Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.5.4 - In cyclic amidines
EC 3.5.4.1 - Cytosine deaminase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.5.4.1
Names
Accepted name:
cytosine deaminase
Other
name:
isocytosine deaminase
Systematic name:
cytosine aminohydrolase
Reaction
- cytosine + H2O = uracil + NH3
Comments:
Also acts on 5-methylcytosine.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0102480
,
GO:0004131
CAS Registry Number:
9025-05-2
UniProtKB/Swiss-Prot:
References
-
The conversion of 5-methyldeoxycytidine to thymidine in vitro and in vivo.J. Biol. Chem. 226 : 631-642 (1957).
-
On the cytosine deaminase of yeast.J. Am. Chem. Soc. 74 : 5157-5160 (1952).
[EC 3.5.4.1 created 1961]