IntEnz

EC 3.5.4.1 - Cytosine deaminase

IntEnz Enzyme Nomenclature
EC 3.5.4.1

Names

Reaction

• 20605 [IUBMB]
  cytosine

  cytosine

  Name origin: UniProt - CHECKED (C)

  CHEBI:16040

  Formula: C4H5N3O
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  H₂O

  H2O

  Name origin: UniProt - CHECKED (C)

  CHEBI:15377

  Formula: H2O
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  =

  NH₄⁺

  NH4(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:28938

  Formula: H4N
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  uracil

  uracil

  Name origin: UniProt - CHECKED (C)

  CHEBI:17568

  Formula: C4H4N2O2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

Comments:

Also acts on 5-methylcytosine.

Links to other databases

References

1. Cohen, S.S. and Barner, H.D.
   The conversion of 5-methyldeoxycytidine to thymidine in vitro and in vivo.
   J. Biol. Chem. 226: 631-642 (1957).
2. Kream, J. and Chargaff, E.
   On the cytosine deaminase of yeast.
   J. Am. Chem. Soc. 74: 5157-5160 (1952).

[EC 3.5.4.1 created 1961]