EC 3 - Hydrolases
EC 3.5 - Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.5.3 - In linear amidines
EC 3.5.3.15 - Protein-arginine deiminase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.5.3.15
Names
Accepted name:
protein-arginine deiminase
Other
names:
peptidylarginine deiminase
PAD
PAD
Systematic name:
protein-L-arginine iminohydrolase
Reaction
-
18089 [IUBMB]H2OName origin: UniProt - CHECKED (C)Formula: H2O
Charge: 0ChEBI compound status: CHECKED (C)L-arginyl-[protein]GENERIC:10532Is ROOT: no
ROOT compound: GENERIC:9624Number of residues: 1=L-citrullyl-[protein]GENERIC:10588Is ROOT: no
ROOT compound: GENERIC:9624Number of residues: 1
Comments:
Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.
Links to other databases
Gene Ontology:
GO:0004668
CAS Registry Number:
75536-80-0
References
-
Properties of peptidylarginine deiminase from the epidermis of newborn rats.J. Biochem. (Tokyo) 89 : 257-263 (1981). [PMID: 7217033]
[EC 3.5.3.15 created 1983]