EC 3 - Hydrolases
EC 3.5 - Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.5.2 - In cyclic amides
EC 3.5.2.9 - 5-oxoprolinase (ATP-hydrolysing)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.5.2.9
Names
Accepted name:
5-oxoprolinase (ATP-hydrolysing)
Other
names:
5-oxo-L-prolinase
5-oxoprolinase
L-pyroglutamate hydrolase
oxoprolinase
pyroglutamase
pyroglutamase (ATP-hydrolysing)
pyroglutamate hydrolase
pyroglutamic hydrolase
5-oxoprolinase
L-pyroglutamate hydrolase
oxoprolinase
pyroglutamase
pyroglutamase (ATP-hydrolysing)
pyroglutamate hydrolase
pyroglutamic hydrolase
Systematic name:
5-oxo-L-proline amidohydrolase (ATP-hydrolysing)
Reaction
- ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0017168
CAS Registry Number:
9075-46-1
References
-
Enzymatic conversion of 5-oxo-L-proline (L-pyrrolidone carboxylate) to L-glutamate coupled with cleavage of adenosine triphosphate to adenosine diphosphate, a reaction in the γ-glutamyl cycle.Proc. Natl. Acad. Sci. USA 68 : 2982-2985 (1971). [PMID: 5289242]
[EC 3.5.2.9 created 1976]