EC - Dihydroorotase

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IntEnz Enzyme Nomenclature


Accepted name:
Other names:
carbamoylaspartic dehydrase
dihydroorotate hydrolase
Systematic name:
(S)-dihydroorotate amidohydrolase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00401
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004151
CAS Registry Number: 9024-93-5
UniProtKB/Swiss-Prot: (344) [show] [UniProt]


  1. Cooper, C. and Wilson, D.W.
    Biosynthesis of pyrimidines.
    Fed. Proc. 13: 194 (1954).
  2. Lieberman, I. and Kornberg, A.
    Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. II. Dihydroorotic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin.
    J. Biol. Chem. 207: 911-924 (1954).

[EC created 1961]