EC 220.127.116.11 - γ-glutamyl-γ-aminobutyrate hydrolase
IntEnz Enzyme Nomenclature
- 4-(gamma-L-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate
Forms part of a novel putrescine-utilizing pathway in Escherichia coli, in which it has been hypothesized that putrescine is first glutamylated to form γ-glutamylputrescine, which is oxidized to 4-(γ-glutamylamino)butanal and then to 4-(γ-glutamylamino)butanoate. The enzyme can also catalyse the reactions of EC 18.104.22.168 (D-glutaminase) and EC 22.214.171.124 (theanine hydrolase).
Links to other databases
A novel putrescine utilization pathway involves γ-glutamylated intermediates of Escherichia coli K-12.J. Biol. Chem. 280 : 4602-4608 (2005). [PMID: 15590624]
[EC 126.96.36.199 created 2006, modified 2011]