EC - γ-glutamylanilide hydrolase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
γ-glutamylanilide hydrolase
Other name:
atdA2 (gene name)
Systematic name:
N5-phenyl-L-glutamine amidohydrolase



The enzyme, characterized from the bacterium Acinetobacter sp. YAA, catalyses the opposite reaction from that cayalysed by EC, γ-glutamylanilide synthase, which is part of an aniline degradation pathway. Its purpose is likely to maintain a low concentration of N5-phenyl-L-glutamine, which is potentially toxic.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Takeo, M., Ohara, A., Sakae, S., Okamoto, Y., Kitamura, C., Kato, D., Negoro, S.
    Function of a glutamine synthetase-like protein in bacterial aniline oxidation via gamma-glutamylanilide.
    J. Bacteriol. 195: 4406-4414 (2013). [PMID: 23893114]

[EC created 2016]