EC 3 - Hydrolases
EC 3.5 - Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.5.1 - In linear amides
EC 3.5.1.12 - Biotinidase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.5.1.12
Names
Accepted name:
biotinidase
Other
names:
amidohydrolase biotinidase
biotinase
biotinase
Systematic name:
biotin-amide amidohydrolase
Reaction
- biotin amide + H2O = biotin + NH3
Comments:
Also acts on biotin esters.
Links to other databases
Protein domains and families:
PROSITE:PDOC50263
Gene Ontology:
GO:0047708
CAS Registry Number:
9025-15-4
UniProtKB/Swiss-Prot:
BTD-2_HUMAN
BTD-3_HUMAN
BTD-4_HUMAN
BTD_BOVIN
BTD_HUMAN
BTD_MOUSE
BTD_RAT
BTD_TAKRU
References
-
Reinigung und Eigenschaften der Biotinidase aus Schweinenieren und Lactobacillus casei.Biochem. Z. 338 : 599-613 (1963). [PMID: 14087327]
-
The enzymatic degradation of soluble bound biotin.J. Biol. Chem. 210 : 569-579 (1954). [PMID: 13211594]
[EC 3.5.1.12 created 1961]