EC 3.5.1.116 - Ureidoglycolate amidohydrolase

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IntEnz Enzyme Nomenclature
EC 3.5.1.116

Names

Accepted name:
ureidoglycolate amidohydrolase
Other names:
ureidoglycolate hydrolase
UAH (gene name)
Systematic name:
(S)-ureidoglycolate amidohydrolase (decarboxylating)

Reaction

Comments:

This plant enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 4.3.2.3, ureidoglycolate lyase, which releases urea rather than ammonia.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Winkler, R.G., Blevins, D.G. and Randall, D.D.
    Ureide catabolism in soybeans. III. Ureidoglycolate amidohydrolase and allantoate amidohydrolase are activities of an allantoate degrading enzyme complex.
    Plant Physiol. 86 : 1084-1088 (1988). [PMID: 16666035]
  2. Wells, X. E., Lees, E. M.
    Ureidoglycolate amidohydrolase from developing French bean fruits (Phaseolus vulgaris [L.].).
    Arch. Biochem. Biophys. 287 : 151-159 (1991). [PMID: 1910298]
  3. Werner, A. K., Romeis, T., Witte, C. P.
    Ureide catabolism in Arabidopsis thaliana and Escherichia coli.
    Nat. Chem. Biol. 6 : 19-21 (2010). [PMID: 19935661]

[EC 3.5.1.116 created 1992 as EC 3.5.3.19, transferred 2014 to EC 3.5.1.116]