EC 3 - Hydrolases
EC 3.5 - Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.5.1 - In linear amides
EC 3.5.1.1 - Asparaginase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 3.5.1.1
Names
Accepted name:
asparaginase
Other
names:
α-asparaginase
L-asparaginase
asparaginase II
colaspase
crasnitin
elspar
leunase
L-asparaginase
asparaginase II
colaspase
crasnitin
elspar
leunase
Systematic name:
L-asparagine amidohydrolase
Reaction
- L-asparagine + H2O = L-aspartate + NH3
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
NIST 74
,
UniPathway
Protein domains and families:
PROSITE:PDOC00132
Gene Ontology:
GO:0004067
CAS Registry Number:
9015-68-3
References
-
Hydrolysis of amides by extracts from mycobacteria.Biochem. J. 65 : 716-720 (1957).
-
Crystalline L-asparaginase from Escherichia coli B.Science 165 : 510-512 (1969).
-
Guinea pig serum and liver L-asparaginases. Comparison of serum and papain-digested liver L-asparaginases.J. Biol. Chem. 245 : 2797-2801 (1970). [PMID: 4987975]
[EC 3.5.1.1 created 1961]