EC 126.96.36.199 - Choriolysin H
IntEnz Enzyme Nomenclature
teleost hatching enzyme (component)
teleost hatching enzyme
high choriolytic enzyme
- Hydrolysis of the inner layer of fish egg envelope. Also hydrolysis of casein and small molecule substrates such as succinyl-Leu-Leu-Val-Tyr┼7-(4-methyl)coumarylamide.
Known from the teleost fish Oryzias latipes (medaka). Efficient dissolution of the egg membrane requires concerted action with choriolysin L. A 25.5 kDa peptidase in family M12 (astacin family).
Links to other databases
Isolation of a choriolytic enzyme (hatching enzyme) of the teleost, Oryzias latipes.Dev. Biol. 29: 343-348 (1972).
Purification and partial characterization of high choriolytic enzyme (HCE), a component of the hatching enzyme of the teleost, Oryzias latipes.J. Biochem. (Tokyo) 105: 204-211 (1989). [PMID: 2656664]
A unique proteolytic action of HCE, a constituent protease of a fish hatching enzyme: tight binding to its natural substrate, egg envelope.Biochem. Biophys. Res. Commun. 162: 58-63 (1989). [PMID: 2751672]
Isolation of cDNAs for LCE and HCE, two constituent proteases of the hatching enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development.Dev. Biol. 153: 250-258 (1992). [PMID: 1397682]
HCE, a constituent of the hatching enzymes of Oryzias latipes embryos, releases unique proline-rich polypeptides from its natural substrate, the hardened chorion.FEBS Lett. 339: 281-284 (1993). [PMID: 8112467]
[EC 188.8.131.52 created 1995]