EC 188.8.131.52 - Stromelysin 2
IntEnz Enzyme Nomenclature
- Similar to stromelysin 1, but action on collagen types III, IV and V is weak.
In peptidase family M10 (interstitial collagenase family). Digests gelatin types I, III, IV, V, fibronectin and proteoglycan.
Links to other databases
Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene.Nucleic Acids Res. 15: 1139-1151 (1987). [PMID: 3547333]
The collagenase gene family in humans consists of at least four members.Biochem. J. 253: 187-192 (1988). [PMID: 2844164]
Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases.Biochemistry 28: 5195-5203 (1989). [PMID: 89352605]
[EC 184.108.40.206 created 1992]