EC - Aspergillopepsin II

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IntEnz Enzyme Nomenclature


Accepted name:
aspergillopepsin II
Other names:
Aspergillus niger var. macrosporus aspartic proteinase
proctase A
proteinase A
Systematic name:



Isolated from Aspergillus niger var. macrosporus, distinct from proteinase B (see aspergillopepsin I) in specificity and insensitivity to pepstatin. In peptidase family A4 (scytalidopepsin B family). Formerly included in EC

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00128
Structural data: CSA , EC2PDB
CAS Registry Number: 9025-49-4


  1. Chang, W.-J., Horiuchi, S., Takahashi, K., Yamasaki, M. and Yamada, Y.
    The structure and function of acid proteases. VI. Effects of acid protease-specific inhibitors on the acid proteases from Aspergillus niger var. macrosporus.
    J. Biochem. (Tokyo) 80 : 975-981 (1976). [PMID: 12156]
  2. Iio, K. and Yamasaki, M.
    Specificity of acid proteinase A from Aspergillus niger var. macrosporus towards B-chain of performic acid oxidized bovine insulin.
    Biochim. Biophys. Acta 429 : 912-924 (1976). [PMID: 1268233]

[EC created 1992 (EC created 1992 (EC created 1961 as EC, transferred 1972 to EC, modified 1981 [EC, EC, EC, EC, EC, EC and EC all created 1972 and incorporated 1978], part incorporated 1992)]