EC 3.4.22.8 - Clostripain

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IntEnz Enzyme Nomenclature
EC 3.4.22.8

Names

Accepted name:
clostripain
Other names:
α-clostridipain
clostridiopeptidase B
Clostridium histolyticum proteinase B
Systematic name:

Reaction

Comments:

From the bacterium Clostridium histolyticum. It requires Ca2+ ions and is inhibited by EDTA. Type example of peptidase family C11. Formerly EC 3.4.4.20.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0051404
CAS Registry Number: 9028-00-6
UniProtKB/Swiss-Prot:

References

  1. Mitchell, W.M.
    Cleavage at arginine residues by clostripain.
    Methods Enzymol. 47: 165-170 (1977). [PMID: 927173]
  2. Gilles, A.-M., Imhoff, J.-M. and Keil, B.
    α-Clostripain. Chemical characterization, activity, and thiol content of the highly active form of clostripain.
    J. Biol. Chem. 254: 1462-1468 (1979). [PMID: 762145]
  3. Gilles, A.-M., Lecroisey, A. and Keil, B.
    Primary structure of α-clostripain light chain.
    Eur. J. Biochem. 145: 469-476 (1984). [PMID: 6391922]

[EC 3.4.22.8 created 1961 as EC 3.4.4.20, transferred 1972 to EC 3.4.22.8]