EC 184.108.40.206 - Papain
IntEnz Enzyme Nomenclature
- Hydrolysis of proteins with broad specificity for peptide bonds, but preference for an amino acid bearing a large hydrophobic side chain at the P2 position. Does not accept Val in P1'.
Links to other databases
Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain.J. Mol. Biol. 182: 317-329 (1985). [PMID: 3889350]
Papain.In: Barrett, A.J., Rawlings, N.D. and Woessner, J.F. (Eds.) Handbook of Proteolytic Enzymes, Academic Press, London, 1998, 555-557
[EC 220.127.116.11 created 1961 as EC 18.104.22.168, transferred 1972 to EC 22.214.171.124, modified 1976, modified 2000]