EC - Streptogrisin B

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IntEnz Enzyme Nomenclature


Accepted name:
streptogrisin B
Other names:
Streptomyces griseus protease B
Streptomyces griseus proteinase 1
Streptomyces griseus proteinase B
Streptomyces griseus serine proteinase B
pronase B
serine proteinase B
Systematic name:



From Streptomyces griseus. A component of Pronase, in peptidase family S1 (trypsin family), distinct from Streptomyces trypsin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00124
Structural data: CSA , EC2PDB
CAS Registry Number: 55071-87-9


  1. Jurasek, L., Fackre, D. and Smillie, L.B.
    Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus.
    Biochem. Biophys. Res. Commun. 37: 99-105 (1969). [PMID: 4899581]
  2. Fujinaga, M., Read, R.J., Sielecki, A., Ardelt, W., Laskowski, M., Jr and James, M.N.G.
    Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey.
    Proc. Natl. Acad. Sci. USA 79: 4868-4872 (1982). [PMID: 6750612]
  3. Read, R.J., Fujinaga, M., Sielecki, A.R. and James, M.N.G.
    Structure of the complex of Streptomyces griseus protease B and the third domain of turkey ovomucoid inhibitor at 1.8-Å resolution.
    Biochemistry 22: 4420-4433 (1983). [PMID: 6414511]
  4. Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T.
    Characterization and structure of genes for proteases A and B from Streptomyces griseus.
    J. Bacteriol. 169: 3778-3784 (1987). [PMID: 3112129]
  5. Greenblatt, H.M., Ryan, C.A. and James, M.N.G.
    Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 Å resolution.
    J. Mol. Biol. 205: 201-228 (1989). [PMID: 2494344]

[EC created 1993]